Virtual Project Update Week

Monday, August 31, 2020 – Friday, September 4, 2020

Please join the Industrial Advisory Board members to review the active 2020 AMBIC projects.

Prerecorded project update videos are posted below. Click the thumbnail of the project you’re interested in to view the video and more information about the project.

Project Update Videos

2016-01: Establishment of AMBIC Reference Cell Lines and Media

2017-02 / 2019-06: Identifying Inhibitory Waste By-Products in High Density CHO Cells

2017-05: Quantifying Process Heterogeneity – Smart Marbles Analytics

2017-06: Project Update — 2017-06: Exploring the Space of CHO Extracellular Vesicles & their Potential Applications

2019-22: Project Update — 2019-22: Nutrient Concentrates: Modeling Media Formulation Strategies for Process Intensification

2017-24: Understanding and Controlling ER Stress in High Secreting CHO Cells

2018-01 Increasing Genomic Stability and Antibody Titer Using Mammalian Artificial Chromosomes

2018-03: Productivity Testing the Targets

2018-06 :Clean CHO

2018-07: Free Metal Ion Activity

2018-18: AMBIC Media Feeding Strategy Design and Testing via a Model-Prediction GUI

2018-28: Establishing Markers for Stability and a Model for Accelerated Prediction of Production (In)stability

2019-42: Project Update — 2019-42: Enhancing Media Solubility and Stability Predictions: Incorporating Hydrogen Bonding Effect and Chemical Complexation

2019-07/13: Metal Speciation in Cultures: Impact on Cell Growth, Productivity, and Quality

2019-12: Enhancing Stability in CHO Cells

2019-10.18: Redox Speciaton and Electrochemical Probing

2019-20: Dipeptides in CHO Culture: Elucidating Uptake Kinetics, Metabolism and Enhanced Solubility

2019-28/30/33: Advanced Manufacturing Platform for Gene Therapeutic Production

On Friday, September 4, PIs will host Office Hours – casual virtual meetings where industrial members can drop in to ask additional questions or discuss project elements if interested. A schedule of the Office Hours is below. You can also access the Office Hours rooms directly using the invite links below.

AMBIC Virtual Project Update Week – PI Office Hours Schedule – September 4, 2020 *all times shown are in EST*
9:00 AM	Bill Bentley – UMD 2017-05: Quantifying Process Heterogeneity – Smart Marble Analytics 2019-10/18: Redox Speciation and Electrochemical Probing in AMBIC Media Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 675 600 252#		9:00 AM
9:30 AM			9:30 AM
10:00 AM	Marc Donohue – JHU 2017-21: Nutrient Concentrates: Modeling Media Formulation Strategies for Process Intensification 2019-42: Enhancing Media Solubility and Stability Predictions: Incorporating Hydrogen Bonding Effect & Chemical Complexation *Join Microsoft Teams Meeting* +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 171 845 625#		10:00 AM
10:30 AM		Marc Birtwistle – CU 2018-01: Increasing Genomic Stability and Antibody Titer Using Mammalian Artificial Chromosomes *Join Microsoft Teams Meeting* +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 647 572 677#	10:30 AM
11:00 AM	Seongkyu Yoon – UML 2017-02: Identifying Inhibitory Waste By-Products in High Density CHO Cells 2018-18: AMBIC Media Feeding Strategy Design and testing via a Model-Prediction GUI 2019-28/30/33: Advanced Manufacturing Platform for Gene Therapeutic Production *Join Microsoft Teams Meeting* +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 251 707 681#		11:00 AM
11:30 AM		Ken Marcus – CU 2019-07/13: Metal Speciation in Cultures: Impact on Cell Growth, Productivity, and Quality Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 108 750 035#	11:30 AM
12:00 PM	Kelvin Lee – UD 2016-01: Establishment of AMBIC Reference Cell Lines and Media 2018-28: Establishing Markers for Stability & a Model for Accelerated Predication of Production (In)stability 2019-28/30/33: Advanced Manufacturing Platform for Gene Therapeutic Production *Join Microsoft Teams Meeting* +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 873 232 030#		12:00 PM
12:30 PM		Mike Betenbaugh – JHU 2017-02: Identifying Inhibitory Waste By-Products in High Density CHO Cells 2018-06: Clean CHO 2018-18: AMBIC Media Feeding Strategy Design and testing via a Model-Prediction GUI 2019-07/13: Metal Speciation in Cultures 2019-20: Dipeptides in CHO culture 2019-28/30/33: Gene Therapy Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 654 938 944#	12:30 PM
1:00 PM	Terry Papoutsakis – UD 2017-06: Exploring the Space of CHO Extracellular Vesicles & their Potential Applications Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 624 144 203#		1:00 PM
1:30 PM		Maciek Antoniewicz – Univ. of Michigan 2018-06: Clean CHO: Targeted Elimination of Secreted By-Products of Amino Acid Catabolism to Improve Volumetric Productivity 2019-20: Dipeptides in CHO culture: elucidating uptake kinetics, metabolism and enhanced solubility *Join Microsoft Teams Meeting* +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 457 789 164#	1:30 PM
2:00 PM	Mark Blenner – CU 2017-24: Understanding and Controlling ER Stress in High Secreting CHO Cells 2018-01: Increasing Genomic Stability and Antibody Titer Using Mammalian Artificial Chromosomes Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 923 874 287#		2:00 PM
2:30 PM		Alan Stone – JHU 2017-10: Characterizing Chemical Complexation 2018-07: Free Metal Ion Activity Determinations in AMBIC Media 2019-07/13: Metal Speciation in Cultures: Impact on Cell Growth, Productivity, and Quality 2019-10/18: Redox Speciation and Electrochemical Probing in AMBIC Media Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 991 887 708#	2:30 PM
3:00 PM	David McNally – UML 2019-28/30/33: Advanced Manufacturing Platform for Gene Therapeutic Production Join Microsoft Teams Meeting+1 443-961-1483 United States, Baltimore (Toll) Conference ID: 997 857 795#		3:00 PM
3:30 PM			3:30 PM
4:00 PM	Chris Saski – CU 2019-12: Enhancing Stability in CHO Cells: The Linkages Between Culture Stress, Chromatin, and Gene Expression Join Microsoft Teams Meeting +1 443-961-1483 United States, Baltimore (Toll) Conference ID: 670 637 413#		4:00 PM
4:30 PM			4:30 PM