Completed Projects

• Elucidating Amino Acid Metabolism in CHO Cells / CleanCHO, 2016
• Understanding and Manipulating the Epigenome to Maximize CHO Cell Productivity, 2016
• Improving Process Understanding through Genome Scale Models and Metabolomics, 2016
• Changes in Host Cell Protein During Extended Cell Culture, 2016
• BOOM-OUR Feed Control for CHO Cell Culture, 2017
• High Throughput Glycan Profiling for Improved Glycosylation Profiles, 2017
• Optimized In-Situ Surface Enhanced Rama Spectroscopy (SERS) for On-Line Monitoring of Cell Culture Metabolites, 2017
• Quantifying Process Heterogeneity – ‘Smart Marbles’ Analytical Technologies, 2017
• Characterizing Chemical Complexation and Speciation in order to Improve Medium and Feed Formulations, 2017
• Controlling Glycosylation and Cell Performance by Inhibiting Genes for the Glycolytic Pathway, 2017
• Determining Genome Stability in CHO Cell Lineages, 2017
• Understanding and Controlling ER Stress in High Secreting CHO Cells, 2017
• Exploring the Space of CHO Extracellular Vesicles and their Potential Applications, 2017
• Characterization of Media Precipitate and Determination of Equilibrium Constants and Precipitation Kinetics, 2018
• Integrated Model of CHO Cell Growth, Substrate Uptake and Intracellular Metabolism for Process Design and Control, 2018